#Xloc 000126 manual
#Xloc 000126 Pc

The results demonstrated that lncRNA XLOC_005950 expression was upregulated in OS tissues and cells. The dual-luciferase reporter assay was performed to confirm the targeting associations between lncRNA XLOC_005950, hsa-miR-542-3p and PFKM. Cell Counting Kit-8 assay, flow cytometry, PFKM activity, and glucose and lactic acid content determination were performed to assess the effects of lncRNA XLOC_005950 knockout and overexpression of hsa-miR-542-3p on the phenotypes of OS cells. CRISPR/Cas9 gene editing was used to knockout lncRNA XLOC_005950 expression in MG63 cells. lncRNA XLOC_005950, hsa-miR-542-3p and PFKM expression in OS tissues and cells was detected via reverse transcription-quantitative PCR analysis. The present study aimed to investigate the involvement of the lncRNA XLOC_005950/hsa-microRNA (miR)-542-3p/phosphofructokinase, muscle (PFKM) axis in the regulation of glucose metabolism, cell proliferation and apoptosis in the progression of OS. However, the effect of long non-coding RNAs (lncRNAs) on glycolysis in osteosarcoma (OS) cells remains unclear. Available in US, Western European and Asian time zones for fastest support.Cancer cells use glucose via glycolysis to maintain tumor cell proliferation. You can access additional, expert resources to streamline your current production environment. The XLOC team can continue to provide file and application configuration to accommodate your production flow. Having a single source of information for all stakeholders saves an incredible amount of time and provides consistent quality.įirst Class Support and Customisation Services Powerful Extended Search and Commenting Featuresĭocument the terminological and stylistic choices, easily and quickly answer questions related to content at any time. XLOC offers on-line, in-line editing for quick changes.Ĭreate speed, efficiency and additional robust workflows users have many choices in how data is edited. Scale your localization efforts by having all language SKU’s developed in-step with your main language development. We continue to enhance our API Integration that allows automation to streamline the development process. XLOC provides the connection between services in the localization production cycle (Translation, LQA, FQA, etc.).Īll key personnel are connected via technology to manage and track the localization effort. Single Environment to Manage all Localization Efforts Audio and Art assets can be uploaded and stored, and Audio assets can be linked and played with corresponding string.Error checking and alignment of data to ensure the integrity of your localized assets.Robust Questions and Answers features allows for team knowledge share.Advanced search and bulk processes simplify workflows.String history and status allows various service lines to track, test and approve localization efforts.Centralised and standardised localization processes for all your projects.

XLOC links the Development and Localization Cycles in a seamless, controlled flow

#Xloc 000126 manual

As a result, the localization cycle can be seamlessly connected to the source content production cycle, pushing to translation just the new and updated content, saving precious time and resources, and eliminating repetitive tasks and errors caused by the manual tracking of assets. XLOC is a key production tool link to enable all global team professionals involved in the development process to collaborate and visualise the status of multilingual assets at any time. Introducing the newest version 6.2 release, XLOC perfects the process of storing, analysing and tracking the evolution of source and localized game assets during the course of development.

#Xloc 000126 Pc

Regardless of whether you are releasing mobile content, AAA console games, or producing continuous MMO PC content, XLOC manages your global assets including text, audio and art, throughout the multilingual game development process. Perfected over 15 years, XLOC is the powerful Content Management System (CMS) dedicated to the development of global video games. XLOC 6.2 - REAL SOLUTIONS FOR GLOBAL GAME DEVELOPMENT